Herpes simplex - Hérpes Simplex
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Herpes simpléks dina biwir.
Hérpes Simplex (Herpes simplex) ― Inféksi herpes simpléks dina ramo langkung umum di barudak ngora tibatan déwasa.
References
Inféksi HSV-1 lumangsung ngaliwatan inféksi primér sél épitél, dituturkeun ku latency, utamana dina neuron, sarta reaktivasi. HSV-1 ilaharna ngabalukarkeun letusan vesicular awal jeung ngulang, utamana dina sungut jeung mukosa séks. Manifestasina rupa-rupa ti herpes orolabial ka sagala rupa kaayaan sapertos folliculitis herpetic, inféksi kulit, keterlibatan ocular, sareng kasus parna sapertos herpes encephalitis. Terapi antiviral mantuan ngatur inféksi HSV.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 2 (HSV-2) mangrupakeun inféksi nyebar, mangaruhan kira-kira 22% tina sawawa umur 12 sarta luhur, jumlahna 45 juta sawawa di Amérika Serikat. Bari HSV-1 ilaharna ngabalukarkeun sores lisan, éta ogé bisa ngakibatkeun lesions séks. Sanajan kitu, lamun penderita boga lesions séks, HSV-2 biasana perhatian utama. Gejala wabah HSV-2 sering kabur, sapertos gatal-gatal séks sareng iritasi, anu tiasa ngalambatkeun diagnosis sareng pengobatan. Tunda ieu tiasa nyababkeun transmisi salajengna ka jalma anu teu katépaan.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus (HSV) ilaharna ngabalukarkeun inféksi kawas herpes séks jeung sores tiis di rumaja jeung déwasa. Nalika HSV nginféksi orok dina 4-6 minggu mimiti kahirupan, éta tiasa nyababkeun panyakit parna sareng akibat anu serius. Diagnosa gancang inféksi HSV neonatal penting pisan pikeun ngeureunkeun panyakit tina parah, nyegah masalah neurologis (malah maot) .
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex Inféksi umum pisan sareng tiasa ditularkeun ti ibu hamil ka orokna. Virus ieu tiasa nyababkeun masalah kaséhatan anu serius atanapi bahkan maot dina bayi anu énggal. Bari éta langka nalika kakandungan sorangan, éta mindeng lumangsung nalika ngalahirkeun. Résiko pangluhurna upami indungna katépaan dina tahap ahir kakandungan. Nanging, résiko ieu tiasa dikirangan ku ngagunakeun obat antiviral atanapi milih bagian C dina kaayaan anu tangtu.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Herpes simplex virus (HSV) jinis 1 sareng 2 nginféksi seueur jalma di dunya. Biasana, virus tetep sepi dina sél saraf saatos nginféksi kulit, tapi tiasa ngaktifkeun deui engké, nyababkeun nyeri tiis. Sakapeung, éta ngabalukarkeun masalah parna sapertos inféksi panon, radang otak, atanapi kaayaan bahaya dina bayi anu anyar lahir sareng jalma anu sistem imun lemah. Sanaos obat-obatan ayeuna ngabantosan ngontrol inféksi, résiko résistansi obat sareng efek samping tetep janten perhatian. Urang peryogi ubar anyar pikeun nargétkeun virus anu langkung saé.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Aya dua jenis virus hérpes simplex (herpes simplex) , tipe 1 (HSV-1) jeung tipe 2 (HSV-2). HSV-1 leuwih ilahar ngabalukarkeun inféksi sabudeureun sungut bari HSV-2 leuwih ilahar ngabalukarkeun inféksi séks. Éta dikirimkeun ku kontak langsung sareng jalma anu katépaan. Herpes séks digolongkeun kana inféksi dikirimkeun séksual. Éta tiasa sumebar ka orok nalika ngalahirkeun. Saatos inféksi, virus diangkut sapanjang saraf indrawi ka awak sél saraf, dimana aranjeunna cicing sapanjang hirup. Anu ngabalukarkeun kambuh tiasa kalebet: turunna fungsi imun, setrés, sareng paparan sinar panonpoé.
Dina kalolobaan kasus, ubar antiviral dicokot ngan lamun gejala parna. Pangobatan antiviral poean tiasa diresepkeun ka jalma anu sering inféksi. Henteu aya vaksin anu sayogi sareng vaksin shingles henteu nyegah herpes simpléks. Pangobatan sareng pangobatan antiviral sapertos aciclovir atanapi valaciclovir tiasa ngirangan parah gejala.
Ongkos sakuliah dunya boh HSV-1 atawa HSV-2 aya antara 60% jeung 95% di sawawa. HSV-1 biasana kainféksi nalika budak leutik. Diperkirakeun 536 juta jalma di sakuliah dunya (16% tina populasi) kainfeksi HSV-2 dina taun 2003 kalayan tingkat anu langkung ageung diantara awéwé sareng jalma-jalma di dunya berkembang. Kalolobaan jalma kalawan HSV-2 teu sadar yen aranjeunna kainféksi.
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